工作经历
2003.8 – 2004.12 香港科技大学电子工程系 博士后2005.2 – 2006.11 美国Purdue University 博士后
2006.12 – 2007.12 美国Michigan State University 博士后
2008.1 – 2009.11 上海交通大学 副教授
2009.12 – 现在 北京大学 特聘研究员
研究方向
超分辨光学显微，超短脉冲多光子成像，新型共聚焦成像技术
主要成就
1）在国际上首次提出利用反射-干涉增强STED的解析度，可同时提升横向和轴向解析度，利用该方法实现了19nm的解析度，刷新了STED在生物样品上的解析度记录（Light， IF 14.6）。首次提出利用贝塞尔-高斯光束结合的STED，实现了155微米的深层超分辨成像，创造了超分辨的探测深度新纪录（LPR，IF 8，封面文章）。
2）利用逆复用多色量子点实现了高速、高标记密度的超分辨（Sci.Rep, IF 5.5）；利用多焦共聚焦实现了三维超分辨(Nano Res., IF 6.9)；合作开发了适合超分辨的单体萤光蛋白（ACS Nano, IF 12.8）。
被评为美国光学会资深会员和OSA成像技术组组长，及中国光学学会生物医学分会常务委员。担任四份SCI期刊编辑（Scientific Reports, Micron, Microscopy Research and Techniques, Chinese Optics Letters），以及Focus On Microscopy组委会委员。
个人作品
Y. Liu, Y. Lu*, X. Yang, X. Zheng, S. Wen, F. Wang, X. Vidal, T. Zhao, D. Liu, Z. Zhou, C. Ma, J. Zhou, J. Piper,P. Xi*, and D. Jin*, “Amplified stimulated emission in upconversion nanoparticles for super resolution nanoscopy,”Nature(2017) doi: 10.1038/nature21366.这一工作得到Chem期刊的点评。
K. Zhanghao, L. Chen, X. Yang, M. Wang, Z. Jing, H. Han, M. Q. Zhang, D. Jin*, J. Gao*,P. Xi*, “Super-resolution with dipole orientation mapping”,Light: Science and Applications (2016).这一工作得到Nature Methods的重点报导（Highlight）。
X. Yang, K. Zhanghao, H. Wang, Y. Liu, F. Wang, X. Zhang, K. Shi, J. Gao, D. Jin, P. Xi*, “Versatile application of fluorescent quantum dot labels in super-resolution fluorescence microscopy”, ACS Photonics, doi: 10.1021/acsphotonics.6b00178 (2016).
X. Yang, H. Xie, E. Alonas, Y. Liu, X. Chen, Q. Ren, P. J. Santangelo, P. Xi*, and D. Jin, “Mirror enhanced axial narrowing super-resolution microscopy”, Light: Science and Applications doi:10.1038/lsa.2016.134 (2016). [2015 Impact factor:14.603]这一工作得到Nature Photonics 2016年7月的重点报导(highlight).
W. Yu, Z. Ji, D. Dong, X. Yang, Y. Xiao, Q. Gong P. Xi*, K. Shi*, “Super-resolution deep imaging with hollow Bessel beam STED microscopy”, Laser Photonics Reviews (2015) doi: 10.1002/lpor.201500151.
X. Zhang, X. Chen, Z. Zeng, M. Zhang, Y. Sun, P. Xi*, J. Peng*, and P. Xu*, “Development of a reversibly switchable protein for super-resolution optical fluctuation imaging”, ACS Nano, 9(3) 2659-2667 (2015). 这一工作得到Science等期刊的多次引用。
X. Chen, Z. Zeng, H. Wang, and P. Xi*, Three dimensional multimodal sub-diffraction imaging with spinning-disk confocal microscopy using blinking/fluctuation probes, Nano Research, 8(7) 2251-2260 (2015).
Z. Zeng, X. Chen, H. Wang, N. Huang, C. Shan, H. Zhang, J. Teng, P. Xi*, Fast Super-Resolution Imaging with Ultra-High Labeling Density Achieved by Joint Tagging Super-Resolution Optical Fluctuation Imaging, Scientific Reports 5, 8359 (2015). 这一工作得到Chem. Soc. Rev.等期刊的高度评价。
X. Yang, Y.-K. Tzeng, Z. Zhu, Z. Huang, X. Chen, Y. Liu, H.-C. Chang, L. Huang, W.-D. Li, and P. Xi*, Sub-diffraction imaging of nitrogen-vacancy centers in diamond by stimulated emission depletion and structured illumination, RSC Advances 4, 11305–11310, (2014). 该工作得到Chem. Soc. Rev. (IF=34.09)，Adv. Opt. Photon.(IF=12.368)等期刊的多次引用。
H. Xie, D. Jin, J. Yu, T. Peng, Y. Ding, C. Zhou, P. Xi*, “Schlieren confocal microscopy for phase-relief imaging”, Opt. Lett., 39(5), 1238-1241, (2014).
Y. Lu, J. Zhao, R. Zhang, Y. Liu, D. Liu, E. M. Goldys, X. Yang, P. Xi, A. Sunna, J. Lu, Y. Shi, R. C. Leif, Y. Huo, J. Shen, J. A. Piper, J. P. Robinson, and D. Jin, Tunable lifetime multiplexing using luminescent nanocrystals, Nature Photonics 8, 32-36 (2014).
J. Zhao, D. Jin, E. P. Schartner, Y. Lu, Y. Liu, A. V. Zvyagin, L. Zhang, J. M. Dawes, P. Xi, J. A. Piper, E. M. Goldys, and T. M. Monro, “Single nanocrystal sensitivity achieved by enhanced upconversion ” Nature Nanotechnology 8(10), 729-734 (2013) doi:10.1038/nnano.2013.171.
Y. Liu, Y. Ding, E. Alonas, W. Zhao, P. J. Santangelo, D. Jin, J. A. Piper,J. Teng, Q. Ren, P. Xi*, “Achieving λ/10 Resolution CW STED Nanoscopy with a Ti:Sapphire Oscillator” , PLoS ONE 7(6) e40003, 2012 (DOI: 10.1371/ journal. Pone. 0040003). 这一工作被评述为“创建了中国第一套STED超分辨系统”。
Y. Ding, H. Xie, T. Peng, Y. Lu, D. Jin, J. Teng, Q. Ren, P. Xi*, “Laser Obique Scanning Optical Microscopy (LOSOM) for Phase Relief Imaging” Optics Express, 20 (13), 14100-14108 (2012).
